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This is a New Brunswick BioFlo 3000 Fermenter with Jacketted Fermentation Vessel.

The New Brunswick BioFlo 3000 Lab Scale Fermenter is an advanced bioprocessing system designed to maximize yields in both fermentation and cell culture.  This fermentor/bioreactor is capable of producing high yields of biomass or secreted products from virtually any microbial, animal, insect and plant cell line. The stirred-tank system comes complete with everything needed for out-of-the-box fermentor start-up, and is offered with a variety of options for dedicated cell culture applications.

The New Brunswick BioFlo 3000 Lab Scale Fermenter is equipped with a thick-walled glass tube fermentor vessel that provides superior resistance to rough handling and repeated autoclaving. This configuration allows for significant reduction in autoclaving time compared to glass-jacketed vessels. For precise temperature control the stainless-steel base has a dished bottom that is jacketed for the circulation of warm or cool water. The New Brunswick BioFlo 3000 Lab Scale Fermenter provides a closed-loop temperature control system without the need for external water baths or circulators.

Easy handling, set-up, and installation are achieved by a detachable motor that readily couples to the agitator without tools, convenient quick-connects for jacket water circulation, and alignment pins that secure the vessel to the console without tools.

The New Brunswick BioFlo 3000 Lab Scale Fermenter screen displays over 75 setpoints and variables. The vacuum fluorescent display provides easy access to every phase of the process, including 13 control loops that simplify start-up, cell growth and process manipulation.

New Brunswick BioFlo 3000 Lab Scale Fermenter Features:

• Built-in Gas-Mixer Optimizes Dissolved Oxygen Levels For High-Density Culture. Two-Gas Mixing in Fermentation provides automatic or manual blending of supplemental oxygen and air. Create air, oxygen, and agitation control cascades that respond to oxygen-demanding microbes, while limiting foam and shear. Four-Gas Mixing in Cell Culture, blends air, oxygen, carbon dioxide, and nitrogen for precise and gentle automatic control of both pH and dissolved oxygen
• 350 mM/L/Hr Oxygen Transfer Rate obtained through powerful fermentation agitation motors and 6-bladed Rushton impellers
• Choice of 12 Interchangeable Vessels. Fermentation vessels offered with or without side ports, in four sizes from 1.6 through 14 liters. Glass-jacketed cell culture vessels, 2.2 through 14 liters total volume
• Stainless-Steel Heat Exchanger forms the rounded bottom of fermentation vessel assemblies. Allows the shortest autoclave time, with no impeding double-insulating glass to slow sterilization. Large-area high-conductivity steel surface provides superior temperature uniformity and the most efficient heat-transfer characteristics. The best choice for fermentation, especially for high-density cultures and for temperature induction
• Vessel Side Ports support chemostat operation
• Optional Low Side Entry Ports (available in fermentor vessels only) - two 19 mm ports in the stainless-steel heat-exchanger support additional probes, which enter the vessel below the impeller. 12 mm adapter available
• Integrated Vessel, Console, Controller and Pumps conserve bench space and simplify connections
• Choice of Thermal Mass Flow Meter or Thermal Mass Flow Controller for accurate air flow monitoring and control
• Tunable P-I Values Optimize DO Control
• Five Assignable, Peristaltic Pumps built in; with control included for optional sixth pump
• Stainless-Steel Exhaust Condenser minimizes media evaporation
• Stainless-Steel Ring Sparger provides uniform distribution of bubbles to impeller blades
• Battery Back-Up retains settings in the event of a power failure